Updates on Eczema and Eczema-Related Research
Non-histamine itch pathway found Histamine, a chemical found in certain white blood cells and in some foods, plays an important role in many types of itch. But antihistamines don’t relieve the chronic itch that patients with eczema endure. Now researchers at Yale and Johns Hopkins have discovered that BAM8-22, a signaling molecule found in the skin, triggers itch in humans via a pathway that does not involve histamine. The receptor to which BAM8-22 binds could be a target for new drugs to turn off the itch of eczema.