Professor of Dermatology Professor of Epidemiology
Blockley Hall Perelman School of Medicine
University of Pennsylvania
What are the main findings of the study?
About half of the US population with atopic dermatitis (AD) are African-American children. Previously described filaggrin mutations are primarily seen in those of European or Asian ancestry. Very rarely are they found in African American children. We found in an African-American cohort with AD, filaggrin-2 (FLG2) mutations were associated with more persistent AD.
WEDNESDAY, Sept. 4 (HealthDay News) -- Women who apply prescription steroid creams such as cortisone to ease a medical issue during pregnancy should not worry that the medication will affect their baby, a new study finds.
"Cortisone [creams] can be a very powerful drug for a pregnant woman suffering from a variety of conditions both related and unrelated to pregnancy," noted one expert, Dr. Doris Day, a dermatologist at Lenox Hill Hospital in New York City.
"In many cases, there are no substitutes that will relieve the itch and suffering of the conditions, which
In a new study published in Nature Genetics, Northwestern Medicine® and Tel Aviv University scientists have found that a structural defect in skin cells can contribute to allergy development, including skin and food allergies, traditionally thought primarily to be a dysfunction of the immune system.
The finding is related to the team’s identification of a new rare genetic disease, called “severe dermatitis, multiple allergies, and metabolic wasting,” or SAM, caused by mutations in the molecule desmoglein 1.
“Desmoglein 1 is best understood as the ‘glue’ that holds the outer layer of human
Some 10 percent of the population suffers from eczema at some point in their lives. The chronic skin condition, for which there are no cures or good treatments, causes symptoms ranging from dry, flaky and itchy skin to flaming red rashes and, particularly in children, nasal allergies and asthma.
Scientists at the University of California, Berkeley, have developed a new picture of how the nervous system interacts with the immune system to cause the itch and inflammation associated with eczema.
New Zealand’s first ever study of occupational dermatitis in cleaners has found rates of eczema among them nearly twice that of people not exposed to cleaning agents.
Centre for Public Health researchers from Massey University’s College of Health measured work-related skin symptoms in 425 cleaners involved in cleaning hospitals, tertiary institutions, schools, commercial buildings and the meatworks industry. Their results were compared with those of non-exposed workers from the retail and clerical sector as well as bus drivers.
Lead research investigator and centre director Professor Jeroen
Mild cases of atopic dermatitis (AD) generally improve with standard treatment. However, standard treatment fails many patients with recalcitrant AD skin lesions. Study results in animal models have demonstrated that the administration of tea (ie, green, black, or oolong) has suppressed type I and type IV allergic reactions.
To test the effectiveness of oolong tea in the treatment of recalcitrant AD.
Although 121 patients with recalcitrant AD were enrolled in the study, 118 patients completed the open study.
Despite their tiny size, bacteria play an important role in eczema and in the overall health of the skin [Hanifin 2009]. beyond the frequent skin infections associated with severe disease, there is the even more important idea that colonizing bacteria—those that are simply residing on the skin—may also directly drive inflammation [Abeck 1998]. Recent studies have found that in patients with atopic dermatitis (AD) the balance of bacteria on the skin is highly abnormal, with a preponderance of “bad” bacteria such as staphylococcus [Lin 2007].
A breakdown of the skin barrier and inflammation in the skin that occurs in eczema could play a key role in triggering food sensitivity in babies, a new study reveals. Scientists say this finding indicates that food allergies may develop via immune cells in the skin rather than the gut, highlighting eczema as a potential target for preventing food allergy in children.
A link between eczema and food allergy has been known for some time, but researchers from King’s College London and the University of Dundee say this study, published in the Journal of Investigative Dermatology, adds to
Probiotics have shown promising potential in reducing the risk of eczema in infants. Optimal probiotic intervention regimen remains to be determined.
We investigated whether maternal probiotic supplementation during pregnancy and breast-feeding reduces the risk of developing eczema in high-risk infants.
This was a parallel, double-blind placebo-controlled trial of 241 mother-infant pairs. Mothers with allergic disease and atopic sensitization were randomly assigned to receive (1) Lactobacillus rhamnosus LPR and Bifidobacterium longum BL999 (LPR+BL999), (2) L
A team led by William Fenical at Scripps Institution of Oceanography at UC San Diego has discovered a new chemical compound from an ocean microbe in a preliminary research finding that could one day set the stage for new treatments for anthrax and other ailments such as methicillin-resistant Staphylococcus aureus (MRSA).
As reported in the international edition of the German journal Angewandte Chemie, Scripps researcher Chris Kauffman in Fenical’s group first collected the microorganism that produces the compound in 2012 from sediments close to shore off Santa Barbara, Calif.
The National Eczema Association provides grants for patient-oriented eczema research. Since 2004, NEA has funded research on topics of primary importance to the eczema sufferer: itch, infection, skin barrier function, prevention and psycho-social aspects of the condition. Many research projects funded by NEA have resulted in multimillion dollar funding from the National Institutes of Health (NIH). This is a tremendous return on our members' investments in NEA's research program!
Contact dermatitis is a condition in which the skin becomes red, itchy, sore, or inflamed after direct contact with a substance. There are two kinds of contact dermatitis: irritant and allergic.
Irritant contact dermatitis
Irritant dermatitis is the most common type. It's caused by contact with acids, alkaline materials such as soaps and detergents, fabric softeners, solvents, or other chemicals. The reaction can look like a red, dry scaly rash, or can look more like a burn.
Other irritants may include:
• Cement • Hair dyes • Long-term exposure to wet diapers • Pesticides or weed
Originally published in Practical Dermatology, December 2012. Edited for patient audience and reproduced with permission.
Although atopic dermatitis (or eczema) is not an easy condition to manage, those with mild to moderate disease can often take solace in the fact that with basic gentle skin care and a few topical medications, they are usually able to combat most flares successfully.
Abstract A study was conducted to compare the Staphylococcus aureus skin colonization of 21 patients with atopic dermatitis (AD) and 22 healthy controls. It was found that the total aerobe count (total CFU/cm2), the S. aureus fraction thereof and the S. aureus carrier frequency were significantly higher in apparently normal skin of AD patients than in healthy individuals. In addition, compared to normal skin of patients S. aureus density was 100 to 1,000 times higher in the 3 different kinds of lesional skin (dermatitic, lichenified and impetiginized sites). 190 S.
Three years into a five-year program, one of the largest eczema research projects in the US still seeks patients, particularly blacks and Hispanics, to volunteer for studies that will link our DNA to our vulnerability to skin infection.
The Atopic Dermatitis Research Network will sequence the whole genomes of 2500 eczema patients and systematically correlate genetic variation with the severity of disease, types of skin infection, and immune status. ADRN scientists are also looking at how eczema may make certain types of vaccination less effective.
In July it will be three years since the NIH awarded National Jewish Health in Denver, CO $31 million to create and administer the Atopic Dermatitis Research Network, a consortium of five academic sites across the US. A contractor, Rho Federal Systems of Chapel Hill, NC, won an $11 million contract to operate a center to coordinate statistics and clinical trials for the project.
That makes $42 million—spread over five years—which puts the project on the large end of NIH funding for individual biomedical efforts.
The National Eczema Association (NEA) no longer considers products that contain fragrance or perfume for inclusion in the Seal of Acceptance program. Products eligible for the NEA Seal of Acceptance are those that have been created or intended for use by persons with eczema or sensitive skin conditions.
Why are fragrances and perfumes of concern?
Almost 20% of the general population is sensitized to at least one allergen and fragrance is one of the most frequently cited substances causing reactions.
Eczema doesn’t respect national borders. It’s something hundreds of millions of people around the world live with. As a patient and blogger I like to keep up with advances made around the world. I have my Google Alerts set up and other feeds open for information. At times it can seem like the world is flat and stuff is happening everywhere at once.
But is it true? Are research advances being made everywhere? The natural way for a reporter or blogger to proceed is to learn about hotspots of innovation and then pay attention to those hotspots.
Neomycin, polymyxin, and bacitracin combination is used to prevent minor skin injuries such as cuts, scrapes, and burns from becoming infected. Neomycin, polymyxin, and bacitracin are in a class of medications called antibiotics. Neomycin, polymyxin, and bacitracin combination works by stopping the growth of bacteria.
How should this medicine be used?
Neomycin, polymyxin, and bacitracin combination comes as an ointment to apply to the skin. It is usually used one to three times a day.
WHAT: National Institutes of Health (NIH) scientists have identified a promising lead for developing a new type of drug to treat infection caused by Staphylococcus aureus, a bacterium that frequently resists traditional antibiotics. The researchers discovered a system used byS. aureus to transport toxins that are thought to contribute to severe staph infections. These toxins—called phenol-soluble modulins (PSMs)—have gained much attention in recent years, but their multitude and diversity have hindered efforts to target them for drug development.
A skin condition that manifests itself in the form of blackheads, whiteheads, pimples and/or cysts; lesions which are thought to result from the accumulation of keratin proteins, bacteria and oil in hair follicles.
A substance that has an opposite reaction to acid and is capable of neutralizing it.
An acquired sensitivity to a substance. When allergic reactions occur following external contact, they usually produce eczema-like dermatitis, usually characterized by redness, itching and swelling.
Antioxidants are substances that may protect your cells against the
Microarray analysis reveals marked intestinal microbiota aberrancy in infants having eczema compared to healthy children in at-risk for atopic disease
Deviations in composition and diversity of intestinal microbiota in infancy have been associated with both the development and recurrence of atopic eczema. Thus, we decided to use a deep and global microarray-based method to characterize the diversity and temporal changes of the intestinal microbiota in infancy and to define specific bacterial signatures associated with eczema.
Background: Increases in allergic diseases have been reported from various epidemiological surveys. However, a few reports demonstrate the comorbidity of food allergy (FA) and allergic march. The aim of this study was to assess the prevalence and comorbidity of allergic diseases in Japanese students. Methods: First-year students (n = 3,321; 2,209 male and 1,112 female) at Osaka University were asked about allergic diseases using postal interview sheets.
Study isn't conclusive, but it's another reason to make healthier choices, expert says
MONDAY, Jan. 14 (HealthDay News) -- Kids who eat fast food three or more times a week are likely to have more severe allergic reactions, a large new international study suggests.
These include bouts of asthma, eczema and hay fever (rhinitis). And although the study doesn't prove that those burgers, chicken snacks and fries cause these problems, the evidence of an association is compelling, researchers say.
"The study adds to a growing body of evidence of the possible harms of fast foods," said study
University of Pennsylvania study for treating the development and severity of atopic dermatitis
The increasing incidence of allergic skin diseases, and the accompanying economic burden and heightened risk of developing other allergic conditions, have spurred researchers to look for better ways to control these immune system-based disorders.
Atopic dermatitis, more commonly called eczema, now affects 10 to 20 percent of children in the United States and direct health-care costs exceed $3 billion, according to the National Institute of Arthritis and
Eczema or Atopic dermatitis (AD) start with an itchy skin rash, but left untreated, can flare up across the entire body. Most sufferers develop symptoms as infants and it affects millions of adults around the world. There is no cure. Managing this chronic illness means applying moisturizing lotions and anti-inflammatory corticosteroids, which can have harmful side effects. A team led by Arup Indra, Associate Professor in the Dept.
The "acid mantle" is a topic not only of historical interest, but also of clinical significance and has recently been linked to vital stratum corneum function. Despite compelling basic science evidence placing skin pH as a key factor in barrier homeostasis, stratum corneum integrity, and antimicrobial defense, application of the acid mantle concept in clinical care is lacking. We review recent basic science investigations into skin pH, discuss skin disorders characterized by aberrant pH, and finally discuss practical application for preservation of the acid mantle.
This product directory contains a listing of Over The Counter (OTC) Drugs which have received the NEA Seal of Acceptance™. Products eligible for the NEA Seal of Acceptance™ are those that have been created or intended for use by persons with eczema or severe sensitive skin conditions and that have satisfied the NEA Seal of Acceptance™ criteria. OTC drugs containing hydrocortisone require special care. Please read the OTC Drug Hydrocortisone FAQ for more information.
Hydrocortisone is a steroid, which works by reducing redness, itching and inflammation. Hydrocortisone is chemically similar to cortisol, a hormone made by your body every day. Topical steroids come in many forms, including ointments, creams, lotions, gels, and tape.
Hydrocortisone is available with or without a prescription. Low-strength preparations (0.5% or 1%), available without a prescription, are used for the temporary relief of itching and rashes caused by eczema among other skin irritations.
NIH-Funded Clinical Study is One of the First to Evaluate Sublingual Immunotherapy as a Peanut Allergy Treatment
A new study supported by the National Institutes of Health (NIH) suggests that sublingual immunotherapy (SLIT) can reduce the allergic response to peanut in adolescents and adults. SLIT is a treatment approach in which, under medical supervision, people place a small amount of allergen under the tongue to decrease their sensitivity to the allergen.
Food allergies are on the rise, affecting 15 million Americans. And according to a new study published in the December 2012 issue of Annals of Allergy, Asthma and Immunology, the scientific journal of the American College of Allergy, Asthma and Immunology (ACAAI), pesticides and tap water could be partially to blame.
The study reported that high levels of dichlorophenols, a chemical used in pesticides and to chlorinate water, when found in the human body, are associated with food allergies.
“Our research shows that high levels of dichlorophenol-containing pesticides can possibly weaken food
Early results from the NIAID-supported Learning Early About Peanut Allergy (LEAP) study show that severe eczema and egg allergy strongly predict risk for peanut allergy. These results may help identify infants who could most benefit from strategies aimed at preventing peanut allergy.
The LEAP study, led by investigators in the United Kingdom, seeks to determine if introducing peanuts early in a child’s diet could prevent future peanut allergy.
We learned from our last blog posting that eczema is a chronic disease. Unfortunately there is no magic pill or treatment for chronic diseases, and there is no cure. Patients with any type of chronic disease learn about lifetime management of the symptoms associated with their disease. Therefore, chronic diseases need long lasting management plans tailored for each individual patient for the disease state that they are in.
We are fortunate that novel research in the area of atopic dermatitis has led to the discovery of many new management approaches, drugs and regimens.
This year’s meeting of the Society of Investigative Dermatology (SID), held in Raleigh, North Carolina, which marked the 75th anniversary of the society, included the first conference dedicated to atopic dermatitis. Drs. Lisa Beck, Professor of Dermatology at University of Rochester Medical Center, and Rebecca Minnillo Executive Director of the SID were instrumental in setting up this meeting. The primary purpose was to begin to identify problems hindering progress in atopic dermatitis research and to establish a research network of like-minded investigators to begin to address these issues.
National Jewish Health (NJH) has received an educational grant from GlaxoSmithKline (GSK) to improve the care of pediatric patients with atopic dermatitis in a medically underserved population. The one-year $586,511 independent medical educational program grant from GSK will be used by NJH to train health care providers and team members from Rocky Mountain Youth Clinics (RMYC) to better diagnose and manage their atopic dermatitis patients, and ultimately improve patient care and quality of life in the Denver metropolitan area.
“Undiagnosed and untreated atopic dermatitis can have a crippling
Since the beginning of this century several studies have been published that have helped to revolutionize our understanding of the pathophysiology of AD. These studies have shown an association between genetic variation and AD. Genes that have been implicated include genes that code proteins associated with skin barrier and genes that code proteins involved in immune function.
The word eczema is derived from a Greek word meaning “to boil over,” which is a good description for the red, inflamed, itching patches that occur during flare-ups of the disease. Eczema is a general term for any type of dermatitis or inflammation of the skin. There are different types of eczema. The most common is called atopic dermatitis (AD).
AD falls into a category of diseases called atopic, a term originally used to describe the allergic conditions asthma and hay fever.
People with eczema—or parents of children with eczema—often suspect that food allergies are somehow setting off eczema flares. But nailing down exactly which foods cause trouble is made difficult by the many other factors that can trigger eczema. Such triggers include emotional or physical stress, environment, and viral or bacterial infection. Recently I spoke on the phone to Jon Hanifin, a professor of dermatology and clinician at Oregon Health Sciences University and NEA board member, to find out whether allergy tests can truly benefit eczema patients.
Q: How often should I be applying topical steroids?
A: Topical corticosteroids are a mainstay of eczema therapy. Sadly, results are often suboptimal because of steroid phobia and mistakes in applying the steroids. The drugs are safe if we focus on two crucial factors: Frequency and Duration.
Here are some suggestions for proper use of topical corticosteroids: * Apply to hydrated skin (after bath, shower or wet compresses). * Generally speaking, and based on your doctor’s directions, begin with twice daily applications for durations of NO more than 3 days for face, eyelids, neck and folds 7 to
Q: Sometimes I don’t follow my doctor’s directions concerning my eczema and steroid medications. What do I need to know to use topical steroids correctly?
A: Managing eczema is confusing; details are important. Doctors complain that patients don’t follow advice. Probably just as often, patients don’t understand what was advised. It’s best to plan a follow-up visit one to two weeks after a steroid is prescribed to clarify instructions and enhance control of eczema if possible. Ask questions and demand clear answers.
Here are some common mistakes to be aware of in topical steroid therapy: * Not
Q: My doctor prescribed topical steroids for my eczema, but I am concerned about using them. Any suggestions?
A: Topical corticosteroids are often the only reasonable therapy for controlling eczema. They are very effective and, if used properly, very safe. A major reason for failure is when there is an inappropriate prescription of low-potency steroids and the starting and stopping of regimens that never really control and stabilize the inflammation.
Q: Aside from dry skin all over my body. The main place I get eczema is on my hands. When I have a flare up it seems to start with small (1-2 centimeter), clear-fluid, blister-type bubbles on my hands. The bubbles pop, the skin underneath is exposed, and the eczema starts. It takes about 7 to 10 days to heal—sometimes more, sometimes less. This depends on how much care I give it. That clear fluid blister that formed comes from something inside my body. Can you help me understand this? What is that clear fluid? I think it may be histamine. What causes it to come out on my hands?
Q: What causes a person to get eczema on his or her body? How can the terrible itch be helped? Are they working on a cure for this awful stuff?
A: Atopic dermatitis is the most common type of eczema and has a genetic basis. Recently discovered genetic defects in the skin barrier seem to account for many, if not most, cases. The defective barrier allows chemical and physical irritants and bacterial toxins to trigger inflammation that causes redness and itching.
Q: What is the Contact Allergen Replacement Database (CARD)? And can I gain access to it without a physician?
A: CARD and CAMP (Contact Allergen Management Program) are databases that can suggest personal care products free of specified allergens. It is impossible for patients or physicians to accurately diagnosis allergic contact dermatitis to the specific components of items that touch the skin without patch testing. Therefore, access to these databases is restricted to patients who have undergone patch testing by a dermatologist.
Q: What is the wet-dry cycle, and why is it bad for eczema?
A: The wet-dry cycle refers to the drying of skin dampened with water or perspiration. Imagine a muddy field: if the sun dries the field quickly, the mud cracks; if it dries slowly on a cloudy day the mud stays smooth. Skin with eczema is especially likely to crack in low humidity conditions when it dries quickly. Applying a moisturizer to slow the drying of wet skin is therefore especially important in the winter when the humidity is lower.
Q: What are allergens, and what are the most common allergens that aggravate eczema?
A: Allergens are any molecule in the environment that can penetrate skin and cause an inflammatory response. Most allergens cause a rash in only a small number of people, but some like poison ivy cause a rash in most people who have skin contact with it. Allergic contact dermatitis usually develops to small, non-protein molecules such as preservatives or metals. Atopic dermatitis patients can also develop contact dermatitis to plant proteins such as oat or dandelion.
Q: What is the difference between atopic dermatitis and contact dermatitis?
A: Atopic dermatitis appears early in life as chapped skin in areas that go through frequent wet-dry cycles (for example, the area around the mouth in babies) or in skin folds. Atopic dermatitis patients are susceptible to skin infections, which often make inflammation worse. Protein molecules, such as foods, or pollen or latex can penetrate broken and inflamed skin, and atopic patients are especially likely to develop an immune response to these types of allergens.
Several years ago, I was diagnosed with atopic dermatitis. The photo shows the rashes on my back, and there were similar rashes on most of the rest of my body. Fortunately I discovered that the problem was chloramine, a mixture of ammonia and chlorine that is used to disinfect the tap water in many areas of the United States (including the San Francisco Bay area, where I live). After I stopped using our water, my skin cleared up completely. I’m sure there are folks with similar problems who are not aware of this chemical and are suffering as a result.
I understand that petroleum is used for eczema-prone skin. However, I don't like to use petroleum. I've tried different balms from spas, and found that I could make my own, using beeswax and oil (olive or almond oil). My latest balm is what I call a Bumble Bee Balm. I've only used it on my own skin, and it works for me. I hope you find it useful, too. I realize this will not be an option for people with certain allergies. I purchased the bee products from Rainbow Groceries in San Francisco.
1/4 ounce beeswax 1 cup oil (olive or almond) manuka honey royal jelly propolis bee
I’d like to share my wish with the Scratch Pad readers.
A Mother’s Wish: Every morning, I try to start the day positively for my daughter’s sake regardless of how much sleep we didn’t get the night before. Today was no exception. I woke her up at 8:25, only three short hours after she finally fell asleep, after the usual night-long restless tossing and turning, scratching, crying, and scratching some more. We were already running late for her big day.
Today, I took my 3-year-old daughter to her first day of preschool, telling myself “she needs this, she will have fun.” My
BOSTON (Aug. 16, 2012) Information presented at American Academy of Dermatology’s Summer Academy Meeting by Lawrence F. Eichenfield, MD, FAAD, a board-certified pediatric dermatologist, chief, division of pediatric and adolescent dermatology and professor of pediatrics and medicine (dermatology), Rady Children’s Hospital and University of California, San Diego School of Medicine. Dr. Eichenfield is also a member of the National Eczema Association Scientific Advisory Committee.
OVERVIEW For the millions of children and adolescents affected by chronic skin conditions such as atopic
Using bioinformatics to mine allergen databases and epidemiological studies, investigators at NIAID have uncovered new information on what makes people allergic to allergens. The NIAID team found that the differences between the structure of foreign proteins and the structure of self-proteins made the foreign ones allergenic. The results of their work appear online in the July 18th issue of PLoS ONE.
Allergic diseases, such as asthma, food allergy, and seasonal allergies, affect millions of people in the United States and seem to be on the rise.
We first learned about atopic dermatitis while studying medicine at Harvard Medical School. It was introduced to us during dermatology lectures where photos of mostly young children where shown with uncomfortable and itchy appearing rashes. At that time, this was another disease that we had to learn and memorize the symptoms and the diagnostic criteria for our exams.
This all changed a few years ago after we started residency and rotated through pediatric dermatology at Children’s Hospital Boston when we actually got to see and interact with the patients and family members of those
To quantify and compare the physiochemical properties of various topical emollients and to correlate these findings with the products' potential to maintain the stratum corneum (SC) acid milieu, while possessing the appropriate water content for skin rehydration, user adherence, and comfort.
MATERIAL AND METHODS:
The pH and hydrophilic fraction of 31 skin moisturizers sold in the US were measured. Hydrophilic Index (HI) was calculated using the "HI equation." The two parameters were charted using a scatter plot with quadrant divisions.
Butyl benzyl phthalate is used in vinyl flooring, artificial leather
By Mary Elizabeth Dallas
Wednesday, June 27, 2012
WEDNESDAY, June 27 (HealthDay News) -- Babies born to women who were exposed to the common household chemical butyl benzyl phthalate (BBzP) during pregnancy are at greater risk for childhood eczema, new research suggests.
BBzP is used in vinyl flooring, artificial leather and other materials, and can be released into the air, the researchers said.
"While hereditary factors, allergens and exposure to tobacco smoke are known to contribute to the condition, our study is the
The US government has ordered 20 million doses of a vaccine that should protect eczema patients from smallpox without exposing them to the risk of developing eczema vaccinatum, a life-threatening infection, according to a press release by the vaccine’s manufacturer, the Danish biotechnology company Bavarian Nordic.
This means that, in the event of a smallpox bioterror attack, instead of relying on the dubious security of herd immunity, people like you and me can get vaccinated. Until the advent of this new vaccine, we could not.
Lisa Beck, a professor of dermatology at the University of Rochester Medical Center (URMC), will soon begin an NIH-funded clinical trial of Actos (pioglitazone), a drug often prescribed for diabetics, which may turn out to strengthen the skin barrier and reduce symptoms for eczema patients.
Actos, made by Takeda Pharmaceuticals and already approved by the FDA in pill form, could appear unofficially on the market for eczema therapy much sooner than a new drug discovered from scratch.
"Experts sometimes use off-label drugs to treat patients with moderate to severe eczema or atopic
SCHAUMBURG, Ill. (May 16, 2012) —The American Academy of Dermatology (Academy) today reiterated the safety and effectiveness of sunscreens to protect against the damaging effects from exposure to ultraviolet (UV) radiation. As one component of a daily sun-protection strategy, sunscreen is an important tool in the fight against skin cancer, including melanoma, the deadliest form of skin cancer.
Unprotected sun exposure is the most preventable risk factor for skin cancer. More than 3.5 million new cases of skin cancer will be diagnosed in the United States this year, affecting 2 million people.
Abstract BACKGROUND: Ectodermal dysplasia (ED) syndromes are a diverse group of disorders that affect multiple ectodermally derived tissues. Small studies and case reports suggest an increase in atopy and primary immunodeficiencies (PIDs) among patients with ED syndromes.
OBJECTIVE: To determine the prevalence of clinical symptoms suggestive of atopy or immunodeficiency among a large cohort of children with ED syndromes.
METHODS: A 9-page questionnaire was mailed to families who were members of the National Foundation for Ectodermal Dysplasias.
National Institutes of Health-funded scientists have determined the genome sequences of a dozen strains of Staphylococcus aureus bacteria known to be resistant to vancomycin, an antibiotic of last resort. The researchers demonstrated -that resistance arose independently in each strain, and identified shared features among the strains that may have helped them acquire vancomycin resistance and evade human immune defenses.
Alternate Routes: Acupuncture, Acupressure and Eczema Kachiu C. Lee, MD and Peter A. Lio, MD
Judging from the increasing media coverage, acupuncture (and its closely-related but needleless cousin, acupressure) has grown in popularity over the past decade (Ernst, 2006). Actress Gwyneth Paltrow (Lantin, 2004) proudly blogs about it on her popular personal website, while Kate Moss openly admits to using acupuncture to assist with smoking cessation (BBC, 2006). But is acupuncture actually effective? Or is it a passing fad? What is the evidence behind acupuncture as a treatment for eczema?
Thefirst ever walk for eczema, the National Eczema Association’s Itching for a Cure 5K, took place on April 28, 2012 in Asheville, North Carolina, and was a tremendous success!
More than 250 walkers of all ages participated on the beautiful University of North Carolina-Asheville campus. WLOS TV Anchor Tammy Watford was the emcee and did a live broadcast from the event. Mix 96.5 WOXL Radio Morning Show Hosts Tammy & Strickland kept the tunes and the crowd going and also had live broadcasts from the event.
The National Eczema Association is grateful for the efforts of Itching for a Cure
To my great delight, a new t-shirt came in the mail the other day. Not only is it the bright sunshine yellow I feel drawn to on these gray winter days, but it also represents a new dawning for NEA. The logo on my yellow t will be on our first official t-shirt for our inaugural fund-raising walk, Itching for a Cure, in April 2012.
Food allergy can be a confusing topic and not all bad reactions to food are actually due to an allergy. If you think you may have a food allergy, discuss it with your doctor.
Food allergy is a common problem affecting as many as 1 in 25 young children but is much less common in adults. Food allergy is more common in people with eczema. Among children under 5 who have eczema, as many as 30% may also have food allergy.
A few vaccines use chicken eggs as a necessary part of the manufacturing process. This is important for you to know if you are allergic to eggs. These vaccines include MMR (Measles, Mumps, and Rubella), MMRV (Measles, Mumps, Rubella, and Varicella), influenza (flu), yellow fever and rabies. Below are the current expert recommendations about receiving these vaccines if you have egg allergy.
I am itching for a cure—a cure for eczema. I know that most readers will know that eczema is a rough, red patch of itchy skin, but do you know that eczema can cover your whole body? Do you know that tiny babies who have eczema sometimes scratch until they bleed? Do you know that many adults get eczema on their hands, causing cracking and soreness that can be debilitating? Most surprisingly, do you know that eczema can lead to feelings of sadness, frustration, and isolation?
Eczema is a chronic itchy skin condition. Eczema usually starts within the first five years of life, most often in the first six months. It typically lasts into childhood and adolescence. In some cases it may last into adulthood. Eczema tends to wax and wane. There are periods of time where the skin appears mildly affected or even normal, alternating with periods of moderate to severe involvement. Some children have very mild eczema and others have severe eczema (also known as atopic dermatitis).
Intendis, a Bayer HealthCare company is the proud sponsor of this Infant and
Good skin care is an essential part of controlling the itch and rash of eczema and sensitive skin. Proper skin care can reduce flare-ups, decrease the need for medication, and improve response to treatment.
When your skin is dry, it is not because it lacks grease or oil, but because it fails to retain water. For this reason, it is important to recognize this and to practice the basic principles of "soak and seal" to achieve good skin care daily.
Gain information, tips, and resources to help you live well with eczema in this monthly e-newsletter. The e-newsletter will provide updates on the Association’s advocacy efforts to increase funding for eczema research, and action you can take. Get the latest news on eczema research, treatment advances and scientific discoveries.
There are 2 topical prescription eczema drugs that do not contain steroids. These are called topical immunomodulators or TIMs. Both are effective in treating the itch and rash of eczema. Neither causes certain side effects, such as thinking of the skin (atophy), or stretch marks (striae), spider veins or discoloration of the skins.
One of them is Elidel® (pimecrolimus). Elidel is a steroid-free cream for patients aged 2 years and older who have mild-to-moderate eczema.
The other topical immunomodulator is Protopic® (tacrolimus). It is a steroid-free ointment for patients aged 2 years and
Good skin care is an essential part of controlling the itch and rash of eczema and sensitive skin. Proper skin care can reduce flare-ups, decrease the need for medication, and improve response to treatment.
The Eczema & Sensitive-Skin Education (EASE) Program is a patient empowerment program that is intended to improve patient outcomes and the quality of life for millions of persons who suffer from eczema and severe sensitive skin conditions. By providing educational tools and resources relating to the care and treatment of eczema and sensitive skin, the EASE Program makes it easier for consumers to navigate the complexity of information directed at eczema and sensitive skin patients and to evaluate the myriad of personal care and household products on the market.
While sometimes it is difficult for patients to vocalize their concerns about eczema, studies show that many patients are not satisfied with their treatment options.
Life Improvements for Eczema (LIFE) is a group of healthcare professionals who are committed to raising awareness about the impact of eczema and assisting people affected by it.
SAN RAFAEL, CA (February 18, 2003) - The National Eczema Association (NEA) today urged anyone who currently has or has ever suffered from eczema or atopic dermatitis not to receive the smallpox vaccine unless they have been exposed to smallpox, because of a heightened risk of life threatening reactions.