There are 2 topical prescription eczema drugs that do not contain steroids. These are called topical immunomodulators or TIMs. Both are effective in treating the itch and rash of eczema. Neither causes certain side effects, such as thinking of the skin (atophy), or stretch marks (striae), spider veins or discoloration of the skins.
One of them is Elidel® (pimecrolimus). Elidel is a steroid-free cream for patients aged 2 years and older who have mild-to-moderate eczema.
The other topical immunomodulator is Protopic® (tacrolimus). It is a steroid-free ointment for patients aged 2 years and older who have moderate-to-severe eczema. Protopic is available in 2 strengths, 0.03% and 0.1%. Both strengths are approved for use in adults; only 0.03% for children aged 2 to 15 years.30